| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 29/05/21 13:30 | CD Teneriffa | Real Oviedo | 2:2 |
| 30/05/21 13:30 | Albacete Balompie | CF Fuenlabrada | 1:2 |
| 30/05/21 16:00 | CD Mirandés | CD Sabadell | 0:2 |
| 30/05/21 16:00 | FC Cartagena | FC Girona | 1:1 |
| 30/05/21 16:00 | Rayo Vallecano | CD Lugo | 0:1 |
| 30/05/21 16:00 | FC Málaga | CD Castellón | 3:0 |
| 30/05/21 16:00 | SD Ponferradina | RCD Mallorca | 2:2 |
| 30/05/21 16:00 | AD Alcorcón | Espanyol Barcelona | 1:0 |
| 30/05/21 16:00 | UD Logrones | UD Las Palmas | 0:1 |
| 30/05/21 16:00 | Real Zaragoza | CD Leganés | 0:5 |
| 30/05/21 16:00 | Sporting Gijón | UD Almeria | 0:2 |